Farideh Halakou

I am pursuing my graduate study in Department of Computer Engineering at Koc University (KU) in Istanbul-Turkey as a teaching and research assistant.  I joined COSBI lab as a PhD student in February 2014 and since then I am working on integrating conformational changes of proteins to traditional PPI networks aiming to understand the phenotypic differences in PPI network level. I also worked on breast cancer lung and brain metastasis PPI network project in which we did diverse topological, functional, and structural analyses for phenotype specificity.

I received my M.Sc. degree in Information Technology Engineering from Kerman Graduate University of Technology (KGUT) under the supervision of Dr. Eftekhari and Prof. Ali Esmailizadeh where I proposed different combinations of filter and wrapper methods for SNP selection.

I received my B.Sc. degree in Computer Engineering from Mirdamad Institute of Higher Education, Gorgan, Iran in 2008.

Research interests

My main research interests are: protein conformational changes, structural analysis of PPI networks, protein surface-interface comparison.


  1. Enriching Traditional Protein-protein Interaction Networks with Alternative Conformations of Proteins. Halakou F, Kilic ES, Cukuroglu E, Keskin O, Gursoy A.  Sci Rep. 2017 Aug 3;7(1):7180.
  2. Topological, functional, and structural analyses of protein-protein interaction networks of breast cancer lung and brain metastases, Halakou F, Gursoy A., Kilic E. S. and Keskin O. 2017 IEEE Conference on Computational Intelligence in Bioinformatics and Computational Biology (CIBCB), Manchester, 2017, pp. 1-7. doi: 10.1109/CIBCB.2017.8058539 ​
  3. Comparison of Hybrid and Filter Feature Selection Methods to Identify Candidate Single Nucleotide Polymorphisms, Farideh Halako, Mahdi Eftekhari, Ali Esmailizadeh, Journal of Computing and Security, July 2014, Volume 1, Number 3 (pp. 205–213)
  4. Feature Selection in Keystroke Dynamics Authentication Systems, Farideh Halakou, International Conference on Computer, Information Technology and Digital Media (CITaDIM2013); 01/2013
  5. ارائه یک روش ترکیبی فیلتر-بسته بندی برای انتخاب SNPهای کاندید, Farideh Halakou, Mahdi Eftekhari, Ali K. Esmailizadeh, Fifth Iran Data Mining Conference; 12/2011
  6. انتخاب چندشکلی های تک نوکلئوتیدی (SNP) مهم با استفاده از ترکیب معیار همبستگی و الگوریتم k-نزدیک ترین همسایه, Farideh Halakou, Mahdi Eftekhari, Ali K. Esmailizadeh, سومين کنفرانس ملي کاربردهاي رياضيات و نظريه کنترل در علوم پزشکي; 11/2011
  7. Using a Hybrid of Correlation Merit, Neural Network and Genetic Algorithm for Selecting Important SNPs, Farideh Halakou, Mahdi Eftekhari, Ali K. Esmailizadeh, Hamid Sanatnama, The 7th National Biotechnology Congress of I.R. Iran; 09/2011
  8. ترکیب ضریب همبستگی و رگرسیون ریج برای انتخاب ویژگی های مهم در بانک اطلاعاتی چند شکلی های تک نوکلئوتیدی (SNP), Farideh Halakou, Mahdi Eftekhari, Ali K. Esmailizadeh, نوزدهمين كنفرانس مهندسي برق ايران 05/2011