Hot Spots of PRotein INTerfaces Database


HotSprint Home

Welcome to Computational Hot Spots of Protein Interfaces (HotSprint) database. Hotsprint gives information about the evolutionary history of the residues on the interface and represents which residues are highly conserved on the interface. In this way, functionally and structurally important residues on the interface can be distinguished.   >> More

For downloading whole data in HotSprint database refer instructions for retrieving HotSprint database.


Search interfaces using pdbId
Enter protein's PDB identifier (e.g. 1yp2) to see its associated interface(s):
Predict hot spots based on
   where score/pScore cutoff >=

pdbId:


Advanced Search
Enter parameters for the interfaces to be matched.
Predict hot spots based on
   where score/pScore cutoff >= 6

Find interfaces having (all conditions are ANDed ):

0 <= <=    number of hotspot residues        <= <= 236
0 <= <=    number of conserved residues    <= <= 192
1 <= <=    average conservation score        <= <= 9
0 <= <=    conserved residue propensity     <= for <= 46.66
0 <= <=    buried accessible surface area    <= <= 19083 (A°²)



Search for information of a structure
Enter chain or PDB identifier (e.g. 1yp2A, 1yp2):

Query:



Contact with the webmaster for any requests. Cosbi, 2007. Last modified on Aug 10, 2007.