Welcome to Computational Systems Biology (COSBI) Group at Koc University
We develop methods and tools for structural biology, and protein-protein interactions.
The list of databases/tools/services developed by our group are:




PRISM protocol : predict protein-protein interactions using protein interfaces

A collection of downloadable programs to predict and structurally model protein-protein interactions (Nat Prot 6, 2011).



P.R.I.S.M. : PRotein Interactions by Structural Matching

PRISM Server is temporarily out of service. A new server will be available soon. Please use the protocol.



HotPOINT : Hot Spot Prediction Server for Protein Interfaces




HotRegion : A database of hot spot clusters




HotSprint: Database of Computational Hot Spots at Protein Interfaces




Interface Dataset 2006



Last modified in March, 2010.
For any problems or comments please send e-mail to CosbiLab.