Welcome to
Computational Systems Biology (COSBI) Group at Koc University
We develop methods and tools for structural biology, and protein-protein interactions.
The list of databases/tools/services developed by our group are:
PRISM protocol : predict protein-protein interactions using protein interfaces
A collection of downloadable programs to predict and structurally model protein-protein interactions (Nat Prot 6, 2011).
P.R.I.S.M. : PRotein Interactions by Structural Matching
PRISM Server is temporarily out of service. A new server will be available soon. Please use the protocol.
HotPOINT : Hot Spot Prediction Server for Protein Interfaces
HotRegion : A database of hot spot clusters
HotSprint: Database of Computational Hot Spots at Protein Interfaces
Interface Dataset 2006
Last modified in March, 2010.
For any problems or comments please send e-mail to
CosbiLab
.